The Pensacola Mountains are a large group of mountain ranges and peaks that extend 280 nautical miles in a northeast–southwest direction in the Transantarctic Mountains System, Queen Elizabeth Land region of Antarctica. They comprise the Argentina Range, Forrestal Range, Dufek Massif, Cordiner Peaks, Neptune Range, Patuxent Range, Rambo Nunataks and Pecora Escarpment. These mountain units lie astride the extensive Foundation Ice Stream and Support Force Glacier which drain northward to the Ronne Ice Shelf.